Expression and function of protease-activated receptor-2 on tumor cells / 肿瘤研究与临床
Cancer Research and Clinic
;
(6): 646-648, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-381825
ABSTRACT
Protease-activated receptor-2 (PAR-2) belongs to the receptor family which is coupled with G-protein. The N-terminus of PAR-2 is cleaved by some proteases to generate a new N-terminus. The new N-terminus can interact with and activate the receptor itself. The update research reported that PAR-2 could be expressed on some cancers as well as tumor cell lines. There are some relationships between the PAR-2 expression and the behaviors of tumor cell, such as proliferation, angiogenesis, migration and invasion.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Cancer Research and Clinic
Year:
2008
Type:
Article
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