Research development on drug resistance of taxol and β tubulin Ⅲ / 肿瘤研究与临床
Cancer Research and Clinic
;
(6): 137-139, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-382695
ABSTRACT
The taxol s effect of inducing apoptosis is mainly related to its ability to promote tubulin polymerization and prevent tubulin chain depolarization. Drug resistance is the main restriction factor for clinical usage of taxol. Some basic and clinical studies support that poor response to taxol and poor prognosis are related to overexpression of β tubulin Ⅲ.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Cancer Research and Clinic
Year:
2011
Type:
Article
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