Research advances of CD+4CD+25 Treg cell and it's function in GVHD / 肿瘤研究与临床
Cancer Research and Clinic
; (6): 718-720, 2010.
Article
in Zh
| WPRIM
| ID: wpr-383141
Responsible library:
WPRO
ABSTRACT
CD+4 CD+25 regulatory T cell (Treg) has immune incompetent and immune suppression functions, and is a kind of suppressor T-cell subsets. It can inhibit the activation and proliferation of CD+4 T cells and CD+8 T cells, so as to effectively suppress the immune system to foreign organ and reduce the graftversus-host disease (GVHD) after hematopoietic stem cell transplantation (HSCT), without affecting the role of graft-versus-leukemia (GVL), which plays an important role in the transplantation immune tolerance.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
Cancer Research and Clinic
Year:
2010
Type:
Article