Relationship between PI3K-Akt signaling pathway and ovarian cancer / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 155-157, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-384386
ABSTRACT
Positive regulative factors of PI3K/Akt signaling pathways is often activated in ovarian cancer, whereas the function of negative regulator PTEN is often defective. These two kinds of regulators cooperatively regulate tumor cell proliferation and apoptosis in closely association with tumor angiogenesis and invasion and metastasis. It has been suggested that PI3K-Akt pathway is not only related to prognosis of tumor patients but can also be used as novel targets for tumor therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2011
Type:
Article
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