Progress of immunologic derangement in the pathogenesis of primary nephritic syndrome / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 68-71, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-384731
ABSTRACT
Help T cell 1/Help T cell 2 and some cytokines disequilibrium can give a suitable explanation for hypersensitivity and hypogammaglobulinemia in primary nephritic syndrome(PNS) patients. The disturbance of regulatory T cell(Treg cell) and Th17 cell can lead to correlated cytokines derangement, which explained the pathogenesis of PNS from another aspect. Refractory nephrotic syndrome can be effectively treated by rituximab followed the percentage of regulatory T cell increasing, which indicated that Treg may play an important role in pathogenesis of PNS.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
Language:
Chinese
Journal:
International Journal of Pediatrics
Year:
2011
Type:
Article
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