Cytokeratin 8 and cancer / 国际肿瘤学杂志

ABSTRACT

Cytokeratin 8 ( CK8 ) belongs to the keratin family of intermediate filament cytoskeletal proteins. A lot of researches have demonstrated that abnormal expression or post-translational modifications of CK8 may affect its activity and consequently affect the development and progression of tumors. Therefore, investigating the role of CK8 in tumorigenesis may contribute to the prevention and treatment of tumors.