An update of nasal-type extranodal nature killer-T-cell lymphoma / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 869-872, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-385698
ABSTRACT
Nasal-type extranodal nature killer-T-cell lymphoma (NKTCL) originates from mature nature killer (NK) cell or NK-like T cell. This lymphoma cells are usually CD3ε, CD56 and Epstein-Barr Virus (EBV) positive and the later plays an important role in the pathogenesis. A number of cell lines and animal models of NKTCL have been established and used in experimental studies. NKTCL always has various chromosome aberrations and the most common is 6q- which are not specific for the disease. Various abnormalities in genes expression and epigenetic also have been found, which might provide potential targets for target therapy in the future.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2010
Type:
Article
Similar
MEDLINE
...
LILACS
LIS