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Autophagy and its role in colorectal pathogenesis and treatment / 国际肿瘤学杂志
Journal of International Oncology ; (12): 774-777, 2010.
Article in Chinese | WPRIM | ID: wpr-386289
ABSTRACT
Autophagy is a catabolic process involving the degradation of a cell's own proteins and organelles and the subsequent recycle of cellular products. Despite the fact that autophagy helps maintain survival, excessive autophagy can lead to autophagic cell death. Recent researches showed that autophagy played an important role in the development, progression and treatment of colorectal cancer;however, the exact mechanisms of autophagy and its effect on chemotherapy and radiotherapy are still under debate.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Etiology study Language: Chinese Journal: Journal of International Oncology Year: 2010 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Etiology study Language: Chinese Journal: Journal of International Oncology Year: 2010 Type: Article