Regression of Choroidal Neovascularization in a Choroideremia Patient after Intravitreal Bevacizumab Injection: A Case Report
Journal of the Korean Ophthalmological Society
;
: 742-745, 2011.
Article
in Korean
| WPRIM
| ID: wpr-38692
ABSTRACT
PURPOSE:
To report the first domestic case of choroidal neovascularization in a choroideremia patient treated with intravitreal bevacizumab injection. CASESUMMARY:
A 29-year-old male presented with a sudden decline in vision in the left eye. Fundus examination revealed areas of choriocapillaries and retinal pigment epithelium atrophy with macular hemorrhage. Fluorescein angiogram revealed vascular hyperfluorescence in the juxtafoveal area. Neurosensory detachment around the macula and increased central macular thickness was also observed using optical coherence tomography. Upon the diagnosis of choroideremia with choroidal neovascularization, the patient was treated with 1.25 mg intravitreal bevacizumab. Visual acuity improved after four injections of intravitreal Bevacizumab with improvement in both detachment and fluorescein leakage.CONCLUSIONS:
In patients with choroideremia presenting sudden decline in vision, ophthalmologists should detect for possible choroidal neovascularization. The results from the present study show that judicious use of intravitreal Bevacizumab may be effective in such cases. Further studies with a large sample size and sufficiently long follow-up periods are required.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Atrophy
/
Vision, Ocular
/
Visual Acuity
/
Choroideremia
/
Follow-Up Studies
/
Choroid
/
Sample Size
/
Fluorescein
/
Choroidal Neovascularization
/
Tomography, Optical Coherence
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Humans
/
Male
Language:
Korean
Journal:
Journal of the Korean Ophthalmological Society
Year:
2011
Type:
Article
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