The changes of IL-6,TNF-α levels in serum and peritoneal fluid of patients with endometriosis / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy
;
(12): 2179-2180, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-387099
ABSTRACT
Objective To study the levels of interleukin-6(IL-6)and tumor necrosis factor-alfa(TNF- α)in serum and peritoneal fluid of women with endometriosis,to explore their roles in pathogenesis of endometriosis. Methods IL-6 and TNF-α levels in peritoneal fluid and serum of 60 patients with endometriosis(34 cases in Ⅰ ~ Ⅱ stage,26 cases in Ⅲ ~ Ⅳ stage)and 30 control cases(not EMS patients)were detected by enzyme linked immunosorbent assay(ELISA). Results Peritoneal fluid and serum levels of IL-6 and TNF-α in EMS group were significantly higher than that in control group(P<0.01),and peritoneal fluid and serum levels of IL-6 and TNF-α in Ⅲ ~Ⅳ stage was siguificantly higher than that in Ⅰ ~ Ⅱ stage(P<0.01). Conclusion IL-6 and TNF-α in peritoneal fluid and serum played an important role in pathogenesis of endometriosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Primary Medicine and Pharmacy
Year:
2010
Type:
Article
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