Investigation in nocturia prevalence, risk factors and quality of life in the Beijing population / 中华泌尿外科杂志

ABSTRACT

Objective To evaluate the prevalence, risk factors of nocturia and nocturia-related quality of life in Beijing area. Methods Age, hypertension, cardiovascular disease, diabetes mellitus, benign prostatic hyperplasia (BPH), alcohol abuse and smoking and nocturia status were analyzed using Logistic analysis. Multiple linear regression analysis was used to identify factors predicting the Nocturia-Quality of Life score. Results 1198 adults completed this query. 411 individuals (34.3%) answered that they arose for urination during night at least twice. The nocturia incidence increased with age from 8.6% in individuals younger than 40 to 67.7% in those older than 70. Hypertension (OR 2.322;95%CI1.387,3.887) and diabetes (OR 2. 298;95%CI1. 066,4. 954) were possible risk factors for nocturia. In male individuals, BPH (OR 3.900;95% CI 1.890,8.049) was another risk factor. Gender was not found associated with nocturia. Increasing nocturia episodes (regression coefficient - 2. 564; 95% CI-3.08,-2.049) and decreasing total sleeping hours (regression coefficient 1.738;95 %CI0.948,2.527) were independent factors predicting a significantly lower N-QOL score. Conclusions Hypertension, diabetes and BPH are associated with nocturia, suggesting that multiple approaches are needed for the treatment of patients with nocturia. Nocturia has significant impact on N-QOL when the patient has two or more episodes per night.