Gamma synuclein and drug resistance in cancer / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 507-510, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-387473
ABSTRACT
Synuclein-γ (SNCG) is overexpressed in many advanced stages cancers, including breast cancer, ovarian cancer, prostate cancer, lung cancer, liver cancer, esophagus cancer, and colon cancer.SNCG stimulates the proliferation, metastasis, and drug resistance of tumor cells, through interacting with BubR1 and damage mitotic checkpoint. A peptic ANK targeted at SNCG can inhibit activity of SNCG and may be developed as an adjuvant therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2010
Type:
Article
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