Oxygen free radical formation during hyperacute rejection in guinea pig to rat xenotransplantation / 中华器官移植杂志
Chinese Journal of Organ Transplantation
;
(12): 58-59, 1996.
Article
in Chinese
| WPRIM
| ID: wpr-387586
ABSTRACT
In order to determine the relationship between hyperacute xenograft rejection and oxygen free radical(OFR)formation,in the model of guinea pig to SD rat cardiac xenotransplantation guinea pig heart specimens were obtained at harvesting,after stored in Ringer's lactate solution(4℃)for 1 hour,and at 60 min after transplantation to assess histological changes and OFR production by light microscopy,electromicroscopy and luminol-enhanced chemiluminescence (LC).OFR formation increased significantlly in hyperacute rejection.These findings suggests that OFR may play important role in the pathogenesis of discordant xenograft rejection.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Chinese Journal of Organ Transplantation
Year:
1996
Type:
Article
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