The incidence of tuberculosis in two children groups after 3-4 years receiving intradermal immunized BCG vaccine with the different doses of 0.05mg and 0.025mg

ABSTRACT

The study was performed in two children groups after 3 - 4 years receiving intradermal immunized BCG vaccine with the different doses of 0.05mg (216 children group I) and 0.025mg (232 childern group II) at some communes in Tu Son, Bac Ninh province and Thanh Tri district, Hanoi city. Results showed that the children malnutrition rate and tuberculosis exposure were the same and there was no statistically significance (P>0.05) in both groups. There were children with IDR (+), IDR > 15 mm, IgM, IgG and IgM antituberculosis, PCR (+) in the rate of children, delayed sensitivity reaction with tuberculin, the abnormal lung X-ray, IgG and IgM antibodies, and the rate of PCR (+). The rate of morbidity of tuberculosis in two children groups was the similar (0.46% and 0.43%, P=0.519). There was no case with meningitis and no statistical difference between two tuberculosis cases.