The prevalence of metabolic syndrome and lifestyle in bipolar disorder patients / 中华行为医学与脑科学杂志

ABSTRACT

Objective To explore the prevalence of metabolic syndrome( MetS) and its components in patients with bipolar disorder and their lifestyle. Methods Collected 148 cases of bipolar disorder in patients with body mass index (BMI),blood glucose,blood pressure,triglyceride(TG),high-density lipoprotein( HDL-C) etc, and self-compiled scale was used to assess their lifestyle. All patients were followed 6 months. The patients werecompared with 65 normal controls. Results The patients group in the baseline period,treatment after 1 months,3 months and 6 months,the incidence of MetS was as followed11.5% ,15.5% ,18.2% ,20.9%. The patients at all stages,the incidence of MetS,BMI≥25kg/m2 ,high TG levels,low HDL-C levels and hypertension were significantly higher than the control (P<0.01). After 6 months of treatment the incidence of MetS,hypertriglyceridemia were higher than baseline (P < 0.05). The patients group' s work intensity, frequency of exercise, eat more than 3 times per day compared with the control group were significantly different (P<0.01, P<0.05). Conclusion The incidence of MetS and hyperuricemia in patients with bipolar disorder after treatment is higher than the control group; as a continuation of the treatment,the incidence of metabolic abnormalities increased gradually. Unhealthy lifestyle, lack of exercise,unreasonable diet maybe increase the risk of metabolic disorders.