Recent Advances in the Development of Experimental Animal Models Mimicking Human Aortic Aneurysms
Vascular Specialist International
;
: 1-10, 2015.
Article
in English
| WPRIM
| ID: wpr-38888
ABSTRACT
Aortic aneurysm is a common and life-threatening disease that can cause death from rupture. Current therapeutic options are limited to surgical or endovascular procedures because no pharmacological approaches have been proven to decrease the chance of expansion or rupture. The best approach to the management of aortic aneurysm would be the understanding and prevention of the processes involved in disease occurrence, progression, and rupture. There is a need for animal models that can reproduce the pathophysiological features of human aortic aneurysm, and several such models have been studied. This review will emphasize recent advances in animal models used in the determination of mechanisms and treatments of aortic aneurysms.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Aorta
/
Aortic Aneurysm
/
Rupture
/
Models, Animal
/
Endovascular Procedures
/
Aneurysm
Limits:
Humans
Language:
English
Journal:
Vascular Specialist International
Year:
2015
Type:
Article
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