Rifampicin-Induced Minimal Change Disease Is Improved after Cessation of Rifampicin without Steroid Therapy
Yonsei Medical Journal
;
: 582-585, 2015.
Article
in English
| WPRIM
| ID: wpr-38890
ABSTRACT
There are several reports to demonstrate that rifampicin, a major anti-tuberculosis agent, is associated with some adverse renal effects, with a few cases of rifampicin-induced minimal change disease (MCD). In the present case, a 68-year-old female presented with nausea, vomiting, foamy urine, general weakness and edema. She had been taking rifampicin for 4 weeks due to pleural tuberculosis. The patient had no proteinuria before the anti-tuberculosis agents were started, but urine tests upon admission showed heavy proteinuria with a 24-h urinary protein of 9.2 g/day, and serum creatinine, albumin, and total cholesterol levels were 1.36 mg/dL, 2.40 g/dL, and 283 mg/dL, respectively. MCD was diagnosed, and the patient achieved complete remission after cessation of rifampicin without undergoing steroid therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Proteinuria
/
Rifampin
/
Tuberculosis, Pleural
/
Remission Induction
/
Treatment Outcome
/
Edema
/
Kidney Function Tests
/
Kidney Glomerulus
/
Antibiotics, Antitubercular
/
Nausea
Limits:
Aged
/
Female
/
Humans
Language:
English
Journal:
Yonsei Medical Journal
Year:
2015
Type:
Article
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