Tuberculous Abscess of the Graft in a Renal Transplant Recipient after Chronic Rejection / 대한이식학회지
The Journal of the Korean Society for Transplantation
;
: 345-347, 1999.
Article
in Korean
| WPRIM
| ID: wpr-38930
ABSTRACT
Tuberculosis is a significant opportunistic infection in transplant recipients under the immunosuppressed condition, though not common and also known to have higher incidence among transplant recipients than in general population. The most common form of tuberculosis among transplant recipients is pulmonary, gastrointestinal, bone and genital tract in decreasing order. However tuberculous infection of the transplanted graft is rare and usually associated with disseminated tuberculosis with high mortality. We experienced M.. tuberculosis infection of the renal allograft after chronic rejection. A 28-year-old female received living-related renal transplantation, required high-dose steroid therapy for two episodes of acute rejection (8 and 20 months later). However, she eventually became renal failure due to chronic rejection and immunosuppression therapy was discontinued. Patient was refered back to our institute for the hemodialysis (post-transplant 40 months) when the patient was found to have pulomary tuberculosis of miliary type. Antituberculosis medication (INH, RFP, EMB & PZA) was immediately started on the basis of positive cultures from lung and bone marrow specimen for M. tuberculosis. In spite of full medication, high fever was sustained and subsequently pyonephritis of grafted kidney was detected and infected graft was removed to confirm the tuberculosis is very serious disease among immunosuppressed transplant patient and therefore more aggressive approach is needed including the search for the hidden infection even at the failed graft with cessated function
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Transplantation
/
Tuberculosis
/
Bone Marrow
/
Opportunistic Infections
/
Incidence
/
Mortality
/
Renal Dialysis
/
Immunosuppression Therapy
/
Kidney Transplantation
/
Transplants
Type of study:
Incidence study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
Language:
Korean
Journal:
The Journal of the Korean Society for Transplantation
Year:
1999
Type:
Article
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