mRNA expressions of chemerin and its receptor 1 in adipose tissue of OLETF rats / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
;
(12): 413-415, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-389869
ABSTRACT
The mRNA expressions of chemerin and its receptor CMKLR1 in adipose tissue of OLETF rats and LETO rats were detected by real-time PCR. The results showed that the two genes mRNA expressions in subcutaneous and visceral adipose tissue in OLETF group were significantly higher than those in LETO group (P< 0.05 or P<0.01) and expressions of them in visceral adipose tissue were higher than those in subcutaneous adipose tissue(P<0. 05 or P<0. 01), suggesting that chemerin and CMKLR1 may be involved in the pathogenesis of obesity, insulin resistance, and type 2 diabetes mellitus.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Endocrinology and Metabolism
Year:
2010
Type:
Article
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