Progress in the pathogenesis of rotavirus-associated disease / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 232-234, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-389920
ABSTRACT
Rotavirus is the most common pathogens of diarrheal diseases in children. Rotavirus infection lead to not only gastrointestinal symptoms but also a variety of extraintesu'nal manifestations. The pathogenesis of RV diarrhea and especially RV viremia is related to multiple factors. Rotavirus infectious diarrhea is related to the damaged cell intercellular connections,the non-structural protein 4, heat shock protein hsc70 and other factors. Pathogenesis of RV viremia may be related to the secretion of inflammatory mediators in vivo and expression of cytokines after RV infection.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
Language:
Chinese
Journal:
International Journal of Pediatrics
Year:
2010
Type:
Article
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