Analysis of etiological agent in 771 children with lower respiratory infection / 国际儿科学杂志

ABSTRACT

Objective To detect and analyze viral pathogens and the etiological agent distribution of hospitalized children with lower respiratory infection. Methods We adopted direct immunofluorescence to detect the seven frequent respirovirus antigens from nasopharyngeal secretion in 771 hospitalized patients with lower respiratory infection.Results Virus detection of 243 cases was positive in 771, the total positives ratio was 31.52%. Respirovirus infection had obviously relation with age and season. The positive rate of virus infection was highest in asthma, followed in bronchiolilis and asthmatic bronchitis, which were 58.80% and 35.56% respectively. Conclusion Different ages and different seasons presented different viral infection and different virus types. Infection rate in infant was higher obviously than that in the other ages, respiratovy syncytial virus and parain- fluenza virus were the major virus in lower respiratory infection. Viral infection was important reason to cause children asthma.