Study of pharyngeal bacterial pathogens of community acquired pneumonia of 359 children / 中国医师进修杂志

ABSTRACT

Objective To investigate the pharyngeal bacterial pathogens of children's community acquired pneumonia(CAP)in hospital,and provide evidences to clinical empirical therapy.Methods Three hundred and fifty-nine patients with CAP were selected.Before the treatment,pharyngeal swabs was taken for culture to find bacteria,then to be done drug sensitivity quantitative test and examed the extended spectrum β lactamages(ESBLs).Results The positive rate was 21.7%(78/359)and bacteria was 82 strains.It was mainly consisted with gram negative bacteria(73.2%,60/82),and klebsiella pneumonia (30.5%,25/82).Streptococcus pneumonia(18.3%,15/82)was the most common in gram positive bacteria.Klebsiella pneumonia was resistant to amoxicillin.Drug resistance of ESBLs producing strains was increased.Streptococcus pneumonia was highly resistant to erythromycin,clindamycin,and tetracycline.The ratio of bacteria infection in infancy age(34.6%.47/136)was higher than others.Conclusions Gram negative bacteria is significant pharyngeal bacterial pathogens in CAP of children.The most common ono is klebsiella pneumonia,and the corresponding one in gram positive bacteria is streptococcus pneumonia.Clinical doctors should avoid using high antibiotic-resistance drugs.