Effects of glimepiride on plasma glucose and beta-cell function in newly diagnosed type 2 diabetic patients / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy
;
(12): 16-17, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-391281
ABSTRACT
Objective To study the effects of glimepiride and short-term intensive therapy with insulin on plasma glucose and beta-cell function in newly diagnosed type 2 diabetic patients.Methods 80 newly diagnosed type 2 diabetic patients were divided into two groups of 40 patients each and randomly treated with insulin or glimepiride plus metformin for 8 weeks.The FBG,2hPBG,HbA_1c,improvement of beta-cell function were measured before and after intensive therapy in each group.Results After the treatment,FBG,2hPBG,HbA_1c were significantly decreased (all P<0.001) in each group;FCP and 2hPCP were increased(P<0.05)in each group.Conclusion Glimepiride or short-term intensive therapy with insulin plus metformin could effectively improve glycemic control and beta-cell function in newly diagnosed type 2 diabetic patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
Chinese Journal of Primary Medicine and Pharmacy
Year:
2010
Type:
Article
Similar
MEDLINE
...
LILACS
LIS