The effect of GRP78 on cancer / 国际外科学杂志
International Journal of Surgery
;
(12): 127-130, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-391545
ABSTRACT
The glucose-regulated protein78 (GRP78) is a member of the heat-shock protein 70 (HSP70) family and responsible for cellular homeostasis. GRP78 is highly expressed in various tumors. It plays an im-portant role in tumor proliferation, survival, metastasis, and drug resistance. Suppression of GRP78 in tumors could enhance cancer treatment. Inhibition of GRP78 in tumors may provide a noval approach toward cancer therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Surgery
Year:
2010
Type:
Article
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