Research progression of microenviroment hypoxia influencing DNA damage-repair in tumour cells / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 812-814, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-392125
ABSTRACT
Microenviroment hypoxia is one of the common phenomenon in cancer,studies have indiacat-ed that hypoxia induces genetic instability via activating many DNA danlage-repair signal pathways,which asso-ciates with tumor invasion and resistance and chemi-radiotherapy resistivity.Here,we overview three main DNA damage-repair pathwaysmismatch repair,homologous recombination and non-homologous end joining,and how hypoxia influences their mechanisms.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2009
Type:
Article
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