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Relationship between ceramide, gastrins and colorectal neoplasms / 国际外科学杂志
International Journal of Surgery ; (12): 612-614, 2009.
Article in Chinese | WPRIM | ID: wpr-392899
ABSTRACT
It is confirmed that expression of gastrins in some colorectal neoplasms cells and their tissue is abnormal. The abnormal expression of gastrins have close relationship with the occurrence and the develop-ment of colorectal neoplasms. Gastrins binding with receptor can regulate ceramides content and promote cells proliferation by series of signal transduction pathways. Blocking these signal transduction pathways may provide a novel therapeutic approach for colorectal neoplasms prevention and treatment.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: International Journal of Surgery Year: 2009 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: International Journal of Surgery Year: 2009 Type: Article