Roles of basic fibroblast growth factor in the seft-renewal of human embryonic stem cells / 国际生物医学工程杂志
International Journal of Biomedical Engineering
;
(6): 251-255, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-393086
ABSTRACT
The self-renewal and multi-lineage developmental potential are the unique properties of human embryonic stem(ES) cells. The growth factors that maintain human or mouse embryonic stem cells are different. Leuckemia inhibitory factor(LIF) does not maintain self-renewal of human ES cells(hESCs). Recently, a few growth factors have been found to be biologically relevant for hESCs functions in vitro, among them the basic fibroblast growth factor(bFGF) is one of the most significant regulators of hESCs self-renewal. The purpose of this review is to introduce the recent progress in the research on the expressions of bFGF and its receptors and their functions in hESCs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Biomedical Engineering
Year:
2009
Type:
Article
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