A case of Sweet syndrome involving the central nervous system / 대한내과학회지
Korean Journal of Medicine
;
: 463-466, 2008.
Article
in Korean
| WPRIM
| ID: wpr-39355
ABSTRACT
Sweet syndrome is an unusual disease characterized by the sudden onset of fever, leukocytosis, and painful erythematous plaques, and the dermal infiltration of neutrophils at the site of skin lesions. Although Sweet syndrome can also present with extra-cutaneous manifestations, involvement of the central nervous system (CNS) is rarely reported. We describe a case of Sweet syndrome involving the CNS in a 46-year-old male with a disturbance of consciousness following fever and erythematous skin plaques in the extremities. Cerebrospinal fluid examination disclosed neutrophilic pleocytosis without decreased glucose and protein levels. HLA typing showed B54, which is frequently seen in Sweet syndrome. Brain magnetic resonance imaging showed abnormal signal intensity lesions in the left temporal lobe. Skin biopsy revealed a dense dermal infiltration of neutrophils, which is compatible with Sweet syndrome. The confused mentality, fever, and erythematous skin plaques resolved after the administration of systemic corticosteroids.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Skin
/
Temporal Lobe
/
Biopsy
/
Brain
/
Histocompatibility Testing
/
Magnetic Resonance Imaging
/
Central Nervous System
/
Sweet Syndrome
/
Consciousness
/
Extremities
Limits:
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2008
Type:
Article
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