Relationship between placental growth factor and acute coronary syndrome / 中国基层医药

ABSTRACT

Objecitve To investigate the relationship between placental growth factor and acute coronary syndrome(ACS). Methods 70 cases of patients with acute chest pain were enrolled. 36 cases of patients who is posi-tive on cardiac troponin T(cTnT) as treatment group, 24 patients who is negative on cTnT as control group, blood of all patients were detected about PLGF and cTnT in hospital,and coromary angiography examination, Gemini score is used to evaluate coronary artery lesion. Result PLGF and cTnT were elevated in ACS, it had significant difference between two groups(P <0. 01) ,PLGF and cTnT are significantly positive correlated(r= 1.2,P <0. 01), PLGF and cornorary artery lesion severity are significantly positive correlated(r = 1 ,P <0. 01). Conclusion PLGF is helpful to predict ACS attack to comorary heart disease,higher PLGF predicts unstable to coronary artery lesion in coronary heart disease.