Effect of globular adiponectin on the function of NIT-I cells under high glucose medium / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
; (12): 316-317, 2009.
Article
in Zh
| WPRIM
| ID: wpr-394223
Responsible library:
WPRO
ABSTRACT
The effect of globular adiponectiin (gAd)on the function of NIT-1 cells under high glucose medium was investigated. The results showed that gad could completely block the increase of NADPH oxidase components p47phox expression and recover mRNA expression of pancreatic duodenal homeobox-I ,paired box gene 6,glucose transpoter 2,and glucokinase except neurogenic differentiation factor 1 (P<0.05 or P<0.01). Whereas,impaired insulin secretion and mRNA expression at high glucose concentration were not significantly improved by gAd.
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Endocrinology and Metabolism
Year:
2009
Type:
Article