Recognition and management of the cardiovascular dysfunction in children with severe hand, foot and mouth disease / 中国小儿急救医学

ABSTRACT

Enterovirus 71 infection was the most important agent related to severe and fatal cases of hand,foot and mouth disease in children. Some severe and fatal cases had cardiovascular dysfunction, which extremely possibly caused by central nervous system involvement and lesions with EV71 infection. But the mechanism was complex and unclear. Monitoring circulation condition and hemodynamic parameters, assessing cardiac function carefully were helpful to detect children at risk of cardiovascular involvement and dysfunction. Early recognition and intervention of children at risk of cardiovascular disorder is the key to rescue severe cases and reduce the mortality.