Relationship between cognitive impairment and arterial stiffness in elderly patients / 中华老年医学杂志
Chinese Journal of Geriatrics
; (12): 374-376, 2009.
Article
in Zh
| WPRIM
| ID: wpr-395087
Responsible library:
WPRO
ABSTRACT
Objective To explore the relationship between cognitive impairment and arterial stiffness in elderly patients. Methods A total of 142 elderly patients were enrolled. Cognitive function was assessed by mini-mental state examination (MMSE) and arterial stiffness was assessed by pulse wave velocity (PWV). A full score on the MMSE was 30, and cognitive impairment was defined as a score less than 24. All subjects underwent the measurement of PWV and MMSE . The subjects were divided into 2 groups: 93 were assigned to the normal cognitive function group (MMSE score 24), and the remainders (n=49) were assigned to the cognitive impairment group (MMSE score 24). Results The PWV was significantly increased in the cognitive impairment group than in the normal cognitive function group [(13.3±2.4) m/s vs. (11.8±2.2) m/s, t=3. 775, P=0. 000]. Logistic regression analysis showed that the PWV was also independently and significantly associated with the MMSE score. Conclusions The increase of arterial stiffness is an important risk factor for impaired cognitive function in elderly patients.
Full text:
1
Index:
WPRIM
Type of study:
Risk_factors_studies
Language:
Zh
Journal:
Chinese Journal of Geriatrics
Year:
2009
Type:
Article