Effect of different treatment methods on left ventricular remodeling after acute myocardial infarction / 中国基层医药

ABSTRACT

Objective To study the effect of captopril combined with metoprolol and captopril alone on improving left ventricular remodeling(LVR)in acute myocardial infarction(AMI).Methods 100 AMI patients were randomly divided into treatment group of 50 cases(captopril combined metoprolol treatment)and 50 cases in the control group(captopril treatment).Using color Doppler ultrasound to deteimine left ventricular shape,configuration and indicators to compare two groups left ventricular remodeling after early(＜2gh);3;6 month end.Results The indices of RaPD;ASL in control group after 6 months end[(63.01±4.10)%and(10.69 ±1.8)cm]were higher than the treatment group[(60.91±3.21)and(10.69±1.8)cm](t=2.121;2.210,all P＜0.05);The LVEF in treatment group after 6 months(51.10±4.60)%were higher than the treatment group(49.10±5,10)%(t=2.231,P＜0.05).Conclusion The captopril combined metoprolol on left ventricular remodeling inhibition significantly better than captopril alone in AMI.