The evealuation of the severity of brain injury and prognosis after neonatal hypoxic-ischemic encephaiopathy / 中国小儿急救医学

ABSTRACT

Objective To study the clinical analysis in the neonatal hypoxic-ischemic encephalopathy (HIE)for evealuation of the severity of brain injury and prognosis. Methods The manifestation,laboratory findings,outcomes of 117 HIE were analyzed. Results Manifestations of HIE in 117 infants included 3 groups(minor level,moderate level,severe level). There was no significant difference in the weight and gestation-age among 3 groups.Scores of Apgar lowing,which Was marked in the severe level(P＜0.01). There was significant difference in the level of pH and PaCO2(P＜0.01). There was significant difference in the level of blood GLU and BE reduced aboviusly in the severe level,and in the level of BUN,CK-MB,CK increased aboviusly in the moderate and severe level,among all(P＜0.01). 69 patients were taked CT on the brain,the abnormal rate of which was 82.6%. The abnormal rate of CT on the brain increased 100% changing with the severity of brain injury on HIE especially in the moderate and severe level. Conclusion The prognosis of the minor level of brain injury on HIE is the best. The prognosis of the moderate-level group who was treated reasonably and enough,is better mostly.