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Analysis of clinical risk factors associated with mortality of severe trauma patients with acute lung injury / 中华急诊医学杂志
Article in Zh | WPRIM | ID: wpr-396875
Responsible library: WPRO
ABSTRACT
Objective To identify the potential risk factors affecting mortality rate of ALl in severe trauma population. Method It was a retrospective cohort study treating trauma as a single cause for emergency depart-ment (ED)) and emergency intensive care unit (EICU) admissions. Eighteen potential risk factors affecting the mortality of ALI were examined by univariate and multivariate logistic analyses in these severe trauma patients. Re-sults There were 343 severe trauma patients with post-traumatic ALI admitted to ED and EICU the Second Affili-ated Hospital Medical College,Zhejiang University,during the study period. The five risk factors that affected the mortality with unadjusted odd ratios (ORs) and 95% confidence intervals (CIs) were (1) APACHE Ⅱ score, (2)duration of trauma, (3) age, (4) aspiration of gastric contents, and (5) DIC. Specific risk factors also affected different patients subpepulations at different degrees. Conclusions Factors of APACHE Ⅱ score and aspiration of gastric contents that can predict the mortality of ALl may exist in the early stage of trauma. Duration of trauma and DIC that greatly affect the short- and long-term development of ALI deserve special attention. Elderly patients (aged beyond 65 years) are the independent risk factor for the secondary sepsis and deterioration of pulmonary function. Patients with these risk factors need aggressive supportive care as early as possible in order to prevent fur-ther aggravation.
Key words
Full text: 1 Index: WPRIM Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Language: Zh Journal: Chinese Journal of Emergency Medicine Year: 2009 Type: Article
Full text: 1 Index: WPRIM Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Language: Zh Journal: Chinese Journal of Emergency Medicine Year: 2009 Type: Article