Angiotensin-Converting Enzyme Gene Polymorphism and Stroke / 国际脑血管病杂志

ABSTRACT

Angiotensin-converting enzyme (ACE) gene is one of major candidate genes with genetic susceptibility to stroke. However, its correlation with stroke remains controversial. The relationship between gene polymorphism and stroke also cannot be determined. A specific branch in the ACE phylogenic tree may replace the insertion/deletion polymorphic site as a risk marker of stroke for association study.