Interaction between hepatic stellate cells and hepatocellular carcinoma / 国际肿瘤学杂志

ABSTRACT

Hepatic stellate cells(HSCs)are key sources of extraeellular matrix during liver fibrosis and in normal liver.During chronic injury,HSCs transform into myofibroblast-like cells,causing liver fibrosis.Hepatocellular carcinoma iS multiple factors disease.There are considerable HSCs infihration in the extracellular matrix of hepatocellular carcinoma.Investigation the interaction between HSCs and hepatocellular carcinoma Can provide a new thinking of hepatocellular carcinoma therapy.