Clinic research of rb-bFGF combined with boric acid solution in treatment of recurrent vulval ulcer / 中国基层医药

ABSTRACT

Objective To explore the effect of recombinant bovine basic fibroblast growth factor(rb-bFGF)combined with boric acid solution on vulval ulcer.Methods 64 patients with vulval ulcer were divided into two groupa randomly.33 patients( group A) with vulval ulcer was treated with rb-bFGF and boric acid solution locally,while the others (group B) accepted ultra-red rays.Before the different treatment above,metronidazole or clotrimasole was put into the vaginae of all the patients,which were given relative medicine according to etiopathogenesis.The two groups were treated continually for two weeks and then were examined.Results The effective rate in group A was significantly higher than that in group B,which was the same result as the ulcer heating time between two groups.Conclusion rb-bGFG combined with boric acid solution is an effective remedy for the treatment of vulval ulcer.