The relativity study of carotid atherosclerosis and morning blood pressure surge / 中国医师进修杂志

ABSTRACT

Objective To investigate the relativity between morning blood pressure surge (MBPS) and carotid atheresclerosis. Methods Noninvasive ambulatory blood pressure monitor (ABPM) was per-formed on 97 patients with the first and second stage of essential hypertension and according the ABPM re-suits, the patients were classified into MP+ group (31 cases) and MP-group (66 cases). In the meantime, the carotid intima-media thickness (IMT) and the carotid atheresclerotic plaque was examined by the color Doppler ultrasound. The relationship among MBPS, carotid atherosclerotic plaque and IMT was analyzed.Results The IMT of common carotid artery (CCA), carotid artery bifurcation (CAB)and internal carotid artery (ICA) in MP+ group was significantly higher than that in MP- group [ (1.02±0.36)mm vs (0.86±0.22) mm, (1.14±0.39 ) mm vs(0.96±0.26) mm, (0.94±0.30 )mm vs ( 0.82±0.18 mm ), P<0.05 ]. The ratio of carotid atherosclerotie plaque in MP+ group was significantly higher than that in MP- group (64.5% vs 42.4%,P<0.05). Conclusions The MBPS is related to carotid atheroselerotie plaque and the carotid IMT. The MBPS may accelerate the forming and developing of atherosclerosis.