Human umbilical cord stromal cells derived from Wharton's jelly / 国际生物医学工程杂志

ABSTRACT

Human umbilical cord stromal cells derived from Wharton's jelly bear the potential of stem cells. They share the common surface markers with mesenchymal stem cells derived from bone marrow. They have a relatively higher proliferation rate and self-renewal capacity and can be successfully differentiated into mature neurons, cardiomyocytes, endothelial, adipocytes, chondrocytes and skeletal cells. Researches have shown their promising foregrounds in regenerative therapeutic applications. This article will give a review about the separation and cultivation methods, in vitro differentiation, and in vitro and in vivo transplantation experiments of the aforementioned stromal cells.