Effects of obesity on insulin resistance, β-cell function and serum high-sensitivity C-reactive protein level in first-degree relatives of type 2 diabetic patients / 中华内分泌代谢杂志

ABSTRACT

Insulin sensitivity,β-cell function and serum high-sensitivity C-reactive protein (hs-CRP)levels were observed in obese and non-obese normoglycemic first-degree relatives of type 2 diabetic patients (FDR). The results showed that there existed insulin resistance,β-cell dysfunction and increased serum hs-CRP level in obese FDR of type 2 diabetic patients. Moreover, insulin resistance and increased CRP level were positively related to waist circumference.