Effect of the combination of two kinds of total flavones on osteoporsis mice / 中国基层医药

ABSTRACT

Objective To study the effects of epimedium koreanum flavones and davallia mariesil flavones on osteoporosis mice induced by retinoie acid.Methods The osteoporosis mice were induced by retinoic acid and then were fed with epimedium koreanum flavones and davallia mariesil flavones.The biochemical markers in serum were observed.Results The data showed that the blood AKP were higher in mice treated with two total flavones than mice in model group,the blood HOP/Cr,BGP,Ca2+ were lower in treated mice than model group(P＜0.01 or P＜0.05).Conclusion This study suggests that those two total flavones can effectively treat the osteoporosis mice induced by retinoic acid.