Dynamic change and prognostic significance of serum IL-18 in a-cute pancreatitis / 国际外科学杂志
International Journal of Surgery
;
(12): 583-586, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-398831
ABSTRACT
Objective To study the dynamic change and prognostic significance of serum IL-18 in acute pancreatitis,and to explore the relationship between the APACHE Ⅱ score and prognosis of. Acute pancreati-tis. Methods According to the clinical diagnosis and criteria for acute pancreatitis, 34 patients with AP were divided into severe acute pancreatitis (SAP) group( n = 12 ) and mild acute pancreatitis (MAP) group (n = 22). Sixteen normal individuals were used as the control group ( n = 16.). The serum IL-18 was detected by ELISA. Results IL-18 in the SAP group was higher than that in the MAP group. In the MAP group, there was significant positive correlation between APACHE Ⅱ and IL-18 ( r = 0.98 ,P < 0.01 ). Conclusion IL-18 plays an important role in the development of acute pancreatitis, and it may be a valuable index to predict the severity of AP.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
International Journal of Surgery
Year:
2008
Type:
Article
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