Effect of nerve growth factor on adrenergic nerve in rals after myocardial infarction / 中国综合临床
Clinical Medicine of China
;
(12): 991-993, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-399102
ABSTRACT
Objective To confirmthe protective effect of nerve growth factor (NGF)on cadiac adrenergie nerve in rats after acute myocardial infarction(AMI)and its mechanism.Methods 120 Wister rats were divided in-to sham-operated group.AMI group and NGF group.The samples were taken after6 h, d,4 d-7 d and 14 d sepa-lately.Immunohistochemistry method WaS used to show the distribution of adrenergic nerve fibers.The density of them were calculated by Medical Pathobgical Image Analysis Processing System.Results ①The densities of adrenergic nerve fibers in AMI group were obviously lower than that of sham-operated group greatly in 6 h and 2 d.4 d-7 d and14 d later.②The densities of adrenergic innervation in NGF group were obviously higher than that of AMI group 7 dand 14 d later.Conclusion NGF has protection effect 011 cardLac adrenergic nerve after AMI in the rat.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Clinical Medicine of China
Year:
2008
Type:
Article
Similar
MEDLINE
...
LILACS
LIS