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Farnesoid X receptor dependent bile acid signaling regulates bile acids metabolism / 国际外科学杂志
International Journal of Surgery ; (12): 565-568, 2008.
Article in Chinese | WPRIM | ID: wpr-399180
Responsible library: WPRO
ABSTRACT
The Farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily and has emerged as a key player in the control of multiple metabolic pathways. Bile acids are the major endogenous ligands for FXR, and by activating FXR have a variety of target genes, many of which are geared toward pre- venting synthesis and uptake and promoting excretion of bile acids. Here we summarized the latest results from studies on FXR target genes and functions in bile acids metabolism in this article.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: International Journal of Surgery Year: 2008 Type: Article
Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: International Journal of Surgery Year: 2008 Type: Article