The correlation between myocardial microcirculation and inflammation in acute myocardial infarction / 中华超声影像学杂志
Chinese Journal of Ultrasonography
;
(12): 672-674, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-399277
ABSTRACT
Objective To investigate the correlation between myocardial microcirculation and inflammation in acute myocardial infarction(AMI)by myocardial contrast echocardiography(MCE).Methods Eighty-one AMI patients(AMI group)and 30 healthy adults(normal control group)were enrolled.White blood cell(WBC),hypersensitive C reactive protein(hsCRP)and neutrophilic gtanulocyte percentage(G%)were measured in patients and healthy adults.According to different count of WBC,AMI group was devided into A group(n=40,WBC≥10×109/L)and B group(n=41,WBC<10×109/L).Myocardial contrast intensity(A),blood flow rate(β)and myocardial blood volume(MBF=A×β)of each segment were measured by MCE during 5-7 days of hospitalization.Results Compared with control group.WBC,hsCRP in A group and hsCRP in B group were significantly elevated(P<0.05).A,β and MBF in A group were significantly lower than those in B group(P<0.05).WBC and hsCRP in A group had significant negative correlations with β respectively(BWBC=-0.67,P<0.05;BhsCRP=-0.5 1,P<0.05).Conclusions The level of plasma inflammatory factors were remarkably increased after AMI,which had a positive correlation with low microcirculation perfusion.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Ultrasonography
Year:
2008
Type:
Article
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