Functions of DNA methyltransferase and methylation in tumor generation / 国际外科学杂志
International Journal of Surgery
; (12): 537-540, 2008.
Article
in Zh
| WPRIM
| ID: wpr-399297
Responsible library:
WPRO
ABSTRACT
Adjustment of epigenetics is closely related with transfer modulation of tumor-related genes. DNA methylation is one of the significant functions of modulation of genetic epigenetics. Abnormal DNA methylation is intensively involved in generation and development of tumor while DNA methylation is cata- lyzed and maintained by DNA methyltransferase(DNMT). So profound study on funetions of DNMT is of great significance to realize generation of abnormal methylation and functions of abnormal methylation in tumor generation and development.
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Index:
WPRIM
Language:
Zh
Journal:
International Journal of Surgery
Year:
2008
Type:
Article