Investigation of retinoic acid in dedifferentiated thyroid carcinoma induction / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
; (12): 295-296, 2008.
Article
in Zh
| WPRIM
| ID: wpr-400122
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WPRO
ABSTRACT
The patients with dedifferentiated thyroid carcinoma were induced by all-trans retinoic acid (ATRA). The treatment was effective in 5 patients (5/9,55.6%), and 5 patients were benefited from following 131 I treatment(5/8, 62.5% ). Three patients(3/12,25.0% ) quitted because of neurological side-effects. It is efficacious to apply ATRA to induce dedifferentiated thyroid carcinoma and improve radio-iodine uptake and acquire benefit for patients, but clinic application of ATRA must be cautious.
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WPRIM
Language:
Zh
Journal:
Chinese Journal of Endocrinology and Metabolism
Year:
2008
Type:
Article