Increased expressions of IL-6 and its receptor gp130 in the thyroid tissues of patients with Graves' disease / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
;
(12): 306-307, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-400211
ABSTRACT
Expressions of interleukin-6 (IL-6) and its receptor (gp80、gp130) in 8 patients with Graves' disease (GD) were compared with those in 8 euthyroid patients with nodular goiter or benign thyroid adenoma. The thyroid tissues of GD expressed significantly higher IL-6 mRNA, gp130 mRNA and IL-6 protein than those of the control group, suggesting that activated IL-6/gp130 signal pathway in the thyroid tissue may contribute to the pathogenesis of GD.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Endocrinology and Metabolism
Year:
2008
Type:
Article
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