Nogo-A and Its Roles in Ischemic Cerebrovascular Disease / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
; (12): 313-316, 2008.
Article
in Zh
| WPRIM
| ID: wpr-400701
Responsible library:
WPRO
ABSTRACT
Myelin-associated inhibitory factor is a major obstacle for axonal regeneration in the central nervous system, and Nogo-A is an important inhibiting factor synthesized by oligoden-drocytes. Toe expression levels of Nogo-A changed significantly in a model of ischemic cere-brovascular disease; the therapeutic measures aiming at Nogo-A and its downstream pathway can effectively enhance axonal regeneration, improve the plasticity of neural structure, and promote functional recovery. This provides a reliable theoretical basis for the development of therapeutic mode in human cerebrovascular diseases.
Full text:
1
Index:
WPRIM
Type of study:
Prognostic_studies
Language:
Zh
Journal:
International Journal of Cerebrovascular Diseases
Year:
2008
Type:
Article